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Shang et al., 2020
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MS may occur in two forms, depending on the presence of psammoma bodies at histological examination [9]
names may vary by market) Tirzepatide (dual GIP/GLP-1 agonist): Mounjaro (type 2 diabetes
Some individuals report nausea, heartburn, or gastrointestinal discomfort when starting GLP-1 therapy, which may interfere with falling or staying asleep
Lifestyle modifications that may help include wearing loose, soft-textured clothing made from natural fibers, using silk or satin bedsheets that produce less friction, maintaining a consistent room temperature to avoid thermal triggers, practicing stress reduction techniques since psychological stress can amplify central sensitization, and optimizing sleep hygiene since poor sleep worsens pain perception
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